"Ancient DNA is like if you put fresh DNA in a 500 degree oven overnight," Dr Rawlence told BBC News. "So what Colossal has produced is a grey wolf, but it has some dire wolf-like characteristics, like a larger skull and white fur," said Dr Rawlence. "A grey wolf is the closest living relative of a dire wolf - they're genetically really similar - so we targeted DNA sequences that lead to dire wolf traits and then edited grey wolf cells... then we cloned those cells and created our dire wolves." According to Dr Rawlence though, dire wolves diverged from grey wolves anywhere between 2.5 to six million years ago. "Colossal compared the genomes of the dire wolf and the grey wolf, and from about 19,000 genes, they determined that 20 changes in 14 genes gave them a dire wolf."
Source:The Times
April 09, 2025 05:45 UTC
Universal, which has made films including Minions and Wicked, has theme parks in Orlando and Los Angeles in the US, as well as in Japan, Singapore and China. The site - which is the former Kempston Hardwick brickworks - will be "one of the largest and most advanced" theme parks on the continent once complete, the production company says. A full planning proposal will be submitted to the UK government, with construction expected to start in 2026. Universal Destinations and Experience said 80% of those employed in the new jobs would be from Bedford, central Bedfordshire, Luton and Milton Keynes. "This is not just about bringing great American creations to Britain, this is also about showcasing great British creations to the world," she told BBC Breakfast.
Source:The Times
April 09, 2025 05:32 UTC
This is your home of Masters tee times and pairings. Who will be looking to make a fast start at Augusta? You’ll find out with our full guide to the 2025 Masters tee times. 2025 Masters tee times: Round 1(US unless stated. 2025 Masters tee times: Round 4:The Round 3 tee times for the 89th Masters will appear here following the conclusion of Round 3.
Source:The Times
April 09, 2025 04:30 UTC
There are many great viewing spots at AugustaThe Masters Par 3 Contest is the traditional prelude to the tournament proper, with players and their families relaxing around Augusta’s short course. Famously, no player has ever won the Par 3 Contest and gone on to win the Green Jacket. Who won the 2024 Masters Par 3 Contest? How long is the Masters Par 3 Contest course? 1st: 130yds2nd: 100yds3rd: 105yds4th: 90yds5th: 155yds6th: 140yds7th: 115yds8th: 120yds9th: 135ydsMasters 2025 Par 3 Contest Tee Times and GroupsAll times EST.
Source:The Times
April 09, 2025 04:26 UTC
London is no longer one of the top five wealthiest cities in the world after losing a higher proportion of millionaires than anywhere other than Moscow. An annual report on global wealth says the UK’s capital has lost 11,300 dollar millionaires over the past year, including 18 centimillionaires and two billionaires. The study, conducted for the advisory firm Henley & Partners by New World Wealth, defines wealth as “liquid investable” assets, which means cash, bonds and shares but excludes property wealth. The assessment was conducted before the recent stock market falls that followed the announcement of Donald Trump’s tariffs. New World Wealth said that London, which
Source:The Times
April 09, 2025 03:05 UTC
Two men have died in a light aircraft crash at a race track. Emergency services were first called to Darley Moor race track at about 11:30 BST on Tuesday and remain at the scene, Derbyshire Police said. People have been urged to avoid the area, which is just over three miles from the town of Ashbourne in Derbyshire. The Air Accidents Investigation Branch (AAIB) has launched an investigation into the crash and flying restrictions are in place.
Source:The Times
April 09, 2025 01:47 UTC
Two boys from Hackney aged 14 and 16 have been charged with criminal damage with intent to endanger life following an incident in Westfield shopping centre in March. They were arrested following reports of furniture being thrown from the top level of the shopping centre in Stratford on 1 March. The pair, who cannot be named because of their ages, will appear at Stratford Youth Court on 6 May. Footage circulated online showed a person launching a seat over a barrier at the shopping centre, narrowly missing bystanders as it plunged down two storeys and onto the ground.
Source:The Times
April 09, 2025 01:27 UTC
Despite being in close proximity to his father, no meeting took place before the King and Queen Camilla departed for a state visit to Italy early Monday.According to sources cited by Fox News Digital, a reunion was "never a realistic option. "Royal commentator Kinsey Schofield was also quoted by Fox News saying, "There is too much tension… the royal family simply cannot trust him today." At the time, Harry expressed hope that the health crisis might mend their strained relationship. Since then, Harry has fought to retain security protection in the UK, arguing he cannot safely visit without it. Meanwhile, Prince Harry’s legal battle continues, with a written verdict on his appeal expected in the coming weeks.
Source:The Times
April 08, 2025 22:31 UTC
WE are just days away from the start of the Masters as the world's best golfers head to Augusta National. Last year, Scottie Scheffler claimed the Green Jacket for the second time in his illustrious career. 2 Scottie Scheffler is the reigning Masters champion Credit: GettyThe World No 1 will join the likes of Nick Faldo and Phil Mickelson should he be victorious at Augusta for a third time. The 21-time major winner has started the 2025 season strongly, winning the Pebble Beach Pro-Am and the Players Championship. The final two days of the Masters will air on CBS with coverage starting at 2pm ET on Saturday and Sunday.
Source:The Times
April 08, 2025 22:07 UTC
The banking hub is located in The Reading Room, in the Laverton on Bratton Road, and will be open from 9am to 5pm from Monday to Friday. READ MORE: New rules at Trowbridge’s M&S car park spark debateThe hub will host a community banker for two days a week, on Tuesday, and Thursday, for NatWest, and Barclays respectively. However, Cash Access also said that a number of other banks will be joining the hub soon. Lloyds is set to join the hub on Mondays; HSBC is set to join on Wednesdays; and Halifax is set to join on Fridays. Gareth Oakley, CEO at Cash Access UK: “I’m happy to announce that we have opened the new banking hub in Westbury, giving local residents renewed access to cash and in-person banking services.
Source:The Times
April 08, 2025 21:50 UTC
Damoh: Where did the man calling himself ‘cardiologist' Narendra John Camm learn how to wield a scalpel, and why did he change his name? "According to police, Camm said that he admitted to creating fake certificates not to forge his qualifications, but to use his Christian name before his visit to the UK in 2000. During interrogation, he insisted that he did his MBBS at North Bengal Medical College. Narendra Vikramaditya Yadav set up Braunwald Healthcare to bring world class healthcare to the poor in India. "He has worked with various hospitals in the past.
Source:The Times
April 08, 2025 17:52 UTC
The landmark number reflects the growing impact of Times Radio’s fast-growing news channel on YouTubeIn the past five years, the Times Radio YouTube channel has seen huge successes covering UK and world politics, global security and real-life stories. From the first piece of content ever posted — an interview with then-Prime Minister Boris Johnson on the day the station launched — the visualised channel for Times Radio now enjoys 58 million views on YouTube every month. “Hitting one billion lifetime channel views is a testament to the focus and hard work done on a daily basis by a video team turning brilliant radio into a brilliant video experience whilst also creating premium audience-focused original content.”Tim Levell, programme director, Times Radio, said: “The growth of video content from Times Radio has been nothing short of extraordinary. Listeners have always loved the intelligent, in-depth interviews on Times Radio, in which presenters give expert guests the space to speak without interruption. The whole team at Times Radio has taken great pleasure in seeing the runaway success of the brand on the world’s dominant video-viewing platform.”
Source:The Times
April 08, 2025 17:34 UTC
Who knew Agent Orange could be so destructive? Not the billionaires who backed Donald Trump — a crew spanning Blackstone’s Steve Schwarzman, the Winklevoss crypto twins and, of course, Elon Musk. Finally, another of his biggest cheerleaders has woken up to the risks of putting untrammelled power into the hands of a US president with wacko economic theories from a bygone age. Rewind to July and there he was bigly endorsing Trump: “I assure you that I have made this decision, carefully, rationally, and by relying on as much empirical data as possible”. Ackman has become the first to publicly break ranks over the tariff mayhem, telling his 1.7 million followers on Musk’s
Source:The Times
April 08, 2025 15:50 UTC
A lawyer for Britain's Prince Harry on Tuesday slammed an "unjustified" decision to downgrade his police protection, telling a London court the prince had recently faced threats from paparazzi and even Al-Qaeda. Lawyer Shaheed Fatima told the court the prince had been "singled out for different, unjustified and inferior treatment." But the prince has said security concerns have hampered his ability to visit Britain, and his trips have usually been fleeting. However, the following month, a judge said Harry could challenge the decision at the Court of Appeal. In its written submission, the government insisted Harry's security "would be considered depending on the circumstances."
Source:The Times
April 08, 2025 15:28 UTC
Citation: Radcliffe E et al (2025) How to deprescribe in primary care and reduce polypharmacy. Advice is available to help clinicians deprescribe during medication reviews – for instance, The King’s Fund’s Polypharmacy and Medicines Optimisation report and Health Improvement Scotland’s polypharmacy guidance. They noted that their study drew on findings from countries where pharmacists do not prescribe and were not usually part of the primary care team. The role of pharmacists in the UK has evolved; evidence suggests that integrating pharmacists into primary care reduces both GP appointments and emergency department attendance, but increases overall use of primary care (Hayhoe et al, 2019). Pharmacists have a central role in deprescribing, but other primary care clinicians, including nurse practitioners and social prescribers, could be involved.
Source:The Times
April 08, 2025 15:18 UTC