worldUpdated: Sep 15, 2020 10:42 ISTInhaled versions of Covid-19 vaccine candidates developed by Oxford University and Imperial College will be trialled to see if they deliver a localised immune response in the respiratory tract, British researchers said on Monday. The Oxford and Imperial vaccines are both being tested in trials through intramuscular injection, but scientists from Imperial said that vaccines delivered via inhalation could potentially deliver a more specialised response. Trials of the Oxford vaccine, which has been licensed to AstraZeneca, resumed at the weekend after safety watchdogs gave it the go-ahead. “We have already shown that (Oxford vaccine) ChAdOx1 nCoV-19 (AZD1222) is safe and induces strong immune responses after intramuscular injection,” said Sarah Gilbert of the University of Oxford. Previous studies suggest that lower doses might be required than in intramuscular injections to give protection, the Imperial researchers said.
Source: Hindustan Times September 15, 2020 05:13 UTC