Three-year-old Nathaniel’s life ‘transformed’ by improvements in genetic tests
Whole genome sequencing provides a readout of a person’s entire genetic code and looks for changes that relate to specific health conditions. One family have described how their son’s diagnosis with a rare condition has given them “power” to help their child. Dr Emma Wakeling, consultant in clinical genetics and genomic medicine at Gosh and study lead, told PA: “We were able to really show quite nicely that the diagnostic rate overall is now significantly better in the diagnostic service that we’re running in the NHS through the Genomic Medicine Service. After his diagnosis Nathaniel now has access to specialist care (handout/PA)“Making a diagnosis earlier in life brings so many benefits to children and their families. “Gaining access to genetic testing and receiving a diagnosis can be vital for families to move forward, both practically and emotionally.”
Source:The Times
December 02, 2025 06:04 UTC
The budget has wrapped your money in even more red tape
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Source:The Times
December 02, 2025 06:03 UTC
The UK’s most delightful libraries, all worth planning a trip around
The Bodleian, OxfordOxford’s Bodleian Library, a must-visit spot for bibliophiles CHRISTOPHER FURLONG/GETTY IMAGESIn terms of English libraries, this is the magnum opus. Gladstone’s Library, Hawarden, FlintshireIf you’re a fan of reading in bed, Gladstone’s Library will be right up your alley: it’s the UK’s only residential library. Leeds Library, LeedsThe Leeds Library moved to its present location in 1808 SIMON MILES PHOTOGRAPHYThis members’ library in Leeds has a special claim to fame: it’s the oldest surviving lending library in the UK, founded in 1768 by a forward-thinking society of northern notables, including its first secretary, the polymath chemist-clergyman-philospher Joseph Priestley. Leeds Art Gallery is just around the corner, while the boutique hotel Dakota Leeds is a quick walk away. Central Library, EdinburghCentral Library overlooks George IV Bridge ALAMYThe Scottish capital has more than 20 libraries, but the blockbuster is the central one.
Source:The Times
December 02, 2025 05:02 UTC
Karoline Leavitt eviscerates New York Times reporter over 'unequivocally false' Trump hit piece
Karoline Leavitt slammed New York Times reporter Katie Rogers over a shocking piece she wrote last week that claimed Donald Trump was showing 'signs of fatigue' in his second term. The press secretary made an example of Rogers' piece about 79-year-old Trump's scaled back public appearances during Monday's White House briefing. 'Oh, same outlet, same reporter who wrote that President Trump is not fit for the job. Leavitt singled out Rogers' piece as part of a new 'Media Offenders' portal of the White House website meant to shame what the White House considers the worst of the 'fake news' media. 'The Creeps at the Failing New York Times are at it again,' Trump told his followers on Truth Social on Wednesday morning.
Source:The Times
December 02, 2025 04:05 UTC
Paddington The Musical we review West End hit show
But the team who have put together this prime slice of family entertainment really have looked after Michael Bond's beloved bear. The cast of Paddington the Musical which is playing at The Savoy Theatre in London. The Brown family with Paddington Bear played by James Hameed and Arti Shah. Victoria Hamilton-Barritt makes a delicious, powerfully-voiced panto baddie as Millicent Clyde the manipulative taxidermist with daddy issues vying to stuff Paddington for posterity. Paddington The Musical runs until further notice at The Savoy Theatre, London.
Source:The Times
December 02, 2025 03:58 UTC
Paddington's West End musical declared a hit by critics
A new stage adaptation of Paddington has received rave reviews from critics following its West End premiere. Paddington the Musical, which features new songs by McFly's Tom Fletcher, follows the beloved bear as he arrives in London and is taken in by the Brown family. The Guardian's five-star review said the show is "imaginatively staged, immaculately performed and utterly winning", while the Telegraph described it as a "funny, feel-good, family-friendly musical that looks set to run and run". Awarding four stars, the Times added: "Break open the marmalade: the West End has a new hit musical that will surely give Matilda a run for its money as a children's favourite."
Source:The Times
December 02, 2025 01:59 UTC
UK and US preparing to strike zero tariffs deal on pharmaceuticals
For free real time breaking news alerts sent straight to your inbox sign up to our breaking news emails Sign up to our free breaking news emails Sign up to our free breaking news emails Email * SIGN UP I would like to be emailed about offers, events and updates from The Independent. Read our Privacy noticeThe UK Government is preparing to strike a deal with the US, securing zero tariffs on pharmaceutical products into the US in return for an increase in NHS spending on American medicines. It comes after warnings that US pharma firms will shut down their sites in the UK if the NHS does not pay more for drugs. The Times reported that the deal will include lowering the sales rebate rate on NHS drug prices. The row has been seen as a reason why US-based Merck and AstraZeneca cancelled or paused investments in the UK in recent months.
Source:The Times
December 02, 2025 00:07 UTC
Rash TV? Zarah Sultana wedded to Married at First Sight
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Source:The Times
December 02, 2025 00:02 UTC
Fashion Awards 2025: Jonathan Anderson crowned designer of the year
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Source:The Times
December 01, 2025 22:44 UTC
OBR chief Richard Hughes resigns after budget leak error
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Source:The Times
December 01, 2025 21:10 UTC
Former Chelsea star, 28, ‘punched and spat at by club ultras in terrifying assault with fan boarding team bus’
FORMER Chelsea star Jeremie Boga was reportedly assaulted by his own fans after ultras boarded the Nice team bus. Fan unrest has grown at the club in recent weeks with the team struggling domestically and in Europe. According to Footmercato, a group of ultras waited for the squad to return to the training ground after landing back in Nice. It is believed 400 supporters showed up to confront the team, with one boarding the team bus. “Here we are losing in Lorient against a team that should be getting relegated.”
Source:The Times
December 01, 2025 20:41 UTC
OBR chief could not rely on chancellor’s support after blunder
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Source:The Times
December 01, 2025 19:52 UTC
Families count the cost of war between Iran and Israel
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Source:The Times
December 01, 2025 19:36 UTC
Sequel to surprise Netflix hit watched over 103,000,000 times is now streaming
As of today, Troll 2 is streaming on the platform for subscribers. Filming took place across Norway, with actress Ine Marie Wilmann taking the lead as palaeontologist Nora Tidemann, while Ameli Olving Sælevik played her younger version. Get personalised updates on all things Netflix Wake up to find news on your TV shows in your inbox every morning with Metro’s TV Newsletter. !’One viewer actually just branded Troll ‘stupid but entertaining,’ which, well, is surely enough to entice anyone, right? Troll 2 is now streaming on Netflix.
Source:The Times
December 01, 2025 18:41 UTC
Man arrested as woman found injured in Broad Street, March
Police were called to Broad Street in March at around 1.45am on Saturday (November 29). Officers had been alerted by the East of England Ambulance Service . A spokesperson for Cambridgeshire Police said: "Officers attended and a man in his 20s was later arrested on suspicion of assault (grievous bodily harm). Have you got a story you want to share? Get in touch at oliver.murphy@newsquest.co.uk or newsdesk@cambstimes.co.uk
Source:The Times
December 01, 2025 18:17 UTC