The genetic mutation that a Chinese researcher claimed he used on a human embryo to create HIV-resistant twins may be linked to a shorter lifespan, according to new research. In November, Shenzhen-based scientist He Jiankui said he had edited the CCR5 gene of the unborn twins to create a mutation that also can occur naturally. The mutation, the Berkeley researchers found, is associated with a 21% increase in mortality later in life. “There both seems to be some beneficial effects of the mutation and some negative effects,” said Nielsen. “I can’t imagine a scenario right now where Crispr editing in embryos is the best option for anything,” Nielsen said.

Source: National Post June 04, 2019 13:42 UTC