In Dogbey's project, the surface of viral vectors will be decorated with disease-specific antibodies using state-of-the-art computational and protein engineering methods. As far back as 2016, Dr Olusiji Alex Akinrinmade - then a PhD student, under Prof Barth - began working on targeted viral vectors. Aside from these, ongoing studies from advanced countries attempted the development of targeted viral vectors to improve gene therapy. The results from this project will provide stakeholders with the technical know-how for preparing next-generation targeted gene delivery cargoes." "The deliverables from this project will include a portfolio of antibody-based targeted gene delivery vectors engineered to make an impact in the cancer gene therapy landscape," said Dogbey.

Source: The North Africa Journal November 12, 2021 20:04 UTC