When used in an animal model, their prototype of a morphine-like molecule was able to produce substantial pain relief in inflamed tissues without severe side effects, according to a study published in the journal Science. The team of researchers used computational simulation to analyse interactions at opioid receptors -- the cell's docking sites for painkillers. Common side effects associated with their use include drowsiness, nausea, constipation and dependency and, in some cases, respiratory arrest. In this study, the the researchers showed that they were able to analyse morphine-like molecules and their interactions with opioid receptors. The new findings could lead to treating postoperative and chronic inflammatory pain without causing side effects.

Source: bd News24 March 04, 2017 11:34 UTC