“We know that a woman’s genetic make-up accounts for about one-third of her risk of developing ovarian cancer. Read moreInherited faults in genes such as the BRCA1 and BRCA2 gene mutations – also known to increase the risk of breast cancer – account for about 40% of the genetic risk. The findings revealed 12 new genetic variants, while confirming the association of 18 of the previously published variants. In total, there are now known to be 30 risk variants, accounting for 6.5% of the inherited component of risk, in addition to the BRCA1 or BRCA2 genes, the researchers said. If we can understand how they work, we will be in a better position to treat, and possibly prevent ovarian cancer,” noted Simon Gayther from Cedars-Sinai Medical Center in Los Angeles, US.
Source: Hindustan Times March 28, 2017 12:56 UTC