Haemophilia A is an inherited, serious disorder in which a person’s blood does not clot properly, leading to uncontrolled and often spontaneous bleeding. “In Malaysia, up to 1,295 persons had haemophilia A in 2017.”She added: “People with haemophilia A can bleed into their muscles and joints, causing difficulty in using them. These antibodies, known as inhibitors, neutralise the factor concentrate given to patient, resulting in ineffective treatment. The Health Ministry approved Hemlibra based on two of the largest clinical studies in people with haemophilia A and factor VIII inhibitors. Meanwhile, interim results from the Haven 2 study, which has 57 patients aged less than 12 years, 54 out of 57 (94.7%) patients had zero treated bleeds.

Source: The Star November 03, 2019 00:00 UTC