Cancers were considered to have a poor prognosis if they had already spread to a regional lymph node or had metastasized to a more distant organ. They also got this designation based on their hormone receptor status. (They qualified if they were estrogen receptor-positive and/or progesterone receptor-positive and HER-2 negative invasive cancers at least 2 centimeters in diameter, triple-negative invasive cancers at least 1 cm in diameter, or HER2-positive invasive cancers at least 1 cm in diameter.)

Source: Los Angeles Times May 03, 2018 15:00 UTC