Scientists, including one of Indian origin, have created the first high-resolution four- dimensional (4D) map of human gene folding, tracking an entire genome as it folds over time. The advance by researchers, including those from Stanford University and Harvard University in the US, may lead to new ways of understanding genetic diseases. In 2014, the same team of scientists showed it was possible to map these loops. In 2015, the team proposed that cohesin creates DNA loops in the cell nucleus by a process of extrusion. In the new research, Aiden, Rao and colleagues tested that assumption.

Source: dna October 07, 2017 08:37 UTC