A new study by a team of researchers from the University of Glasgow, United Kingdom and the Gladstone Institutes, San Francisco, have revealed that eating a diet high on saturated fats might make depression more likely. AdvertisingThe research team led by Prof. George Baillie, from the University of Glasgow conducted a preliminary study where they fed a high-fat diet, containing up to 60% of both saturated and unsaturated fats to mouse models. It seems the high levels of this acid in the hypothalamus alter a signaling pathway, known as cAMP/PKA, is linked to depression. The fatty acids can directly modulate the signalling pathway that is responsible for the development of depression. These findings suggest that the influx of saturated fatty acids due to the consumption of a high-fat diet can alter the signalling cascade and result in the development of depression phenotype.

Source: Indian Express May 15, 2019 12:45 UTC