SaveCommentary: It’s in your DNAIt is almost impossible to pick up a medical journal today without seeing an article or commentary on gene editing. The GEI — directed by Eric Kmiec, PhD — allows me to see and learn the progress and complexities of gene editing. To protect themselves against invaders, the bacteria capture pieces of a virus in DNA and store them as segments called crispers. If the same invader tries to attack again, those DNA segments help an enzyme called Cas find and slice up the invader’s DNA. The approach combines elements of CRISPR and prime editing with a pair of enzymes designed to enable the integration of large segments of DNA without incurring double-stranded DNA breaks.

Source: The Guardian May 11, 2024 09:46 UTC