The study suggests that exposure to chemical compounds called xenoestrogens may significantly reduce the effectiveness of anti-oestrogen treatments for cancer. (Source: File Photo)Oestrogen-mimicking compounds found in breads, soybean and a range of commonly consumedgrains can reverse the effects of ‘breakthrough’ drug therapy used to treat breast cancer, scientists have found. Researchers used advanced metabolomics technology to analyse the effects of palbociclib/letrozole on breast cancer cells. The analysis revealed that neither palbociclib alone nor letrozole alone had a strong effect on metabolites in an ER- positive breast cancer cell line. Under the influence of either xenoestrogen, the breast cancer cells also resumed proliferating at a rate comparable to that seen in the absence of drug treatment.

Source: Indian Express January 15, 2018 12:37 UTC