You can certainly mirror your existing 1TB hard drive to a 1TB Flash drive. At best, it might help you to get up and running after you replaced the failed hard drive, but so would keeping a back-up on an external hard drive. It also offered Windows PE (Preinstallation Environment), which ran a minimal version of Windows from a USB Flash drive. That should get you back to work pretty quickly after a hard drive failure, but you’d only want to use it until you could get a proper hard drive replacement. USB flash drives are marked as being removable, which means the operating system treats them differently from local hard drives.
Source: The Guardian November 09, 2017 12:04 UTC