46A: “Program opening?” sounds like the first number in a concert, but here we’re thinking about software and hardware. The answer is CD DRIVE, because it’s an opening in your computer where you insert the CDs (or used to insert the CDs; is this a “Hi, kids”?) 5D: I liked seeing CHUTZPAH in the grid, and I suppose that “Arguing with God” would take a good amount of it. When you see a clue like “Apt surname for an acupuncturist,” the constructor and editors are looking for a name that might sound like something having to do with the subject. When I finally filled it in, I discovered that the answer to this was PBRS, and I didn’t even know what they were.
Source: New York Times December 15, 2018 03:00 UTC