Weight loss jabs could leave users 'worse off than before' if they pile fat back on when they stop taking them, researchers warn. Weight loss jabs are a class of drugs known as GLP-1 receptor agonists, which work by mimicking the hormone GLP-1 to regulate blood sugar levels and suppress appetite. Researchers said the findings, published in eClinicalMedicine, 'indicate that there is significant weight regain following cessation of GLP-1RAs'. Researchers called for future trials to explore the the effect of GLP-1RAs on the composition of weight loss during and after treatment. Steven Luo, also an author on the study, said: 'When stopping weight loss drugs, doctors and patients should be aware of the potential for weight regain and consider ways to mitigate this risk.

Teacher Darragh Traynor has been working in Qatar for three years and said there were explosions going off every 45 minutesIrish citizens across the Middle East say they feel “trapped”, “terrified” and “completely in the dark” as tensions between the US, Israel and Iran intensify and airlines ground flights. In Doha, 27‑year‑old primary school teacher Darragh Traynor, originally from Co Fermanagh and now in his third year working in Qatar, described the moment the first barrage hit on Saturday.

I have €60,000 in savings and my expenses are lowA €20,000 car loan would cost about €400 per month over five years. Photo: Getty/Michael GleesonI’m in my mid-20s and have been driving a 2013 Honda Civic (200,000km on the clock) for the past six years. I spend around €125 a month on fuel thanks to its excellent efficiency.

OpenAI, the company behind ChatGPT, is on track to lose $14bn this year. A grassroots boycott called QuitGPT has been spreading across the US and beyond, asking people to cancel their ChatGPT subscriptions. Employees of ICE — the agency whose agents killed two people in Minneapolis in January — have used a screening tool powered by ChatGPT. Every month, subscription money from users around the world flows to a company that is embedding itself in the repressive infrastructure of the Trump administration. It is about rejecting the idea that we have no choice but to fund a company that’s bankrolling authoritarianism.

Donald Trump's commanders have been accused of telling troops that the war with Iran is part of God's plan for Armageddon. The complaints span more than 40 different units across 30 military sites, first reported on veteran journalist Jonathan Larsen's Substack. The troops are currently outside the Iran theater but on 'ready-support' status, meaning they could be deployed at any time. A White House official denied that commanders were giving orders based on end times scripture, adding that the war had three aims: destroy Iran's missiles, munitions industry and navy. Trump initially said the war would last four to five weeks but has since warned it could go on 'far longer.'

Joao Pedro scored a hat-trick as Chelsea boosted their Champions League qualification hopes with a handsome 4-1 win at Aston Villa. When Luiz struck inside three minutes, Villa had high hopes of taking a huge step towards securing their own Champions League ambitions but their night turned sour. But it was Chelsea who went in at half-time in front as Pedro struck again in the sixth minute of time added on. Villa were getting picked apart and Pedro claimed the match ball in the 64th minute with his hat-trick goal. Garnacho could have made it five from another counter-attack, but he shot straight at Martinez.

Viewers of last Friday’s Late Late Show may have missed a brief notice just before the show aired in relation to this week’s schedule. It announced there will be a break from the regular schedule this Friday, March 6, with host Patrick Kielty and co taking a rare Friday night off. There was no explanation at the time, but RTÉ has confirmed to the Irish Examiner that they expect regular viewers will instead be cheering on the rugby at that time.

Bernardo Silva calls out referees after damaging Man City draw - 'We know how it works'Manchester City were held to a 2-2 draw by Nottingham Forest as they lost ground in the Premier League title race - and Bernardo Silva was furious with the officiatingView 2 Images Bernardo Silva raged at the officials post-match (Image: TNT Sports)Bernardo Silva hit out at referee Darren England and VAR officials after Manchester City’s title hopes were severely dented by Nottingham Forest. ‌The City skipper claimed Matz Sels brought Erling Haaland down when the home side were 2-1 ahead in the second half. ‌Silva fumed: “The Erling incident? Nothing more to say, I said it in the past.”FOLLOW OUR MAN CITY FB PAGE! After five games in 15 days, it is not easy to perform at this level, but there were good moments of football, good team spirit and I’m happy with my players.

Killeigh's Keira Shand wins first place at RTE'S This is Art! competitonKilleigh's Keira wins first place at RTÉ’s This is Art! competitionA young Offaly artist has been announced as the first-place winner in the Age 8 to 11 category of RTÉ’s This is Art! The annual all-island competition invited young people aged 18 and under to respond to this year’s theme: This is Nature! Second and third-place winners receive bursaries to further develop their artistic practice.

Offaly photographer's work features in new wetlands publicationThe work of one of Offaly’s best-known nature photographers features in a new guide for wetlands communities involved in creative projects. The publication is part of an effort to engage and enthuse local people to get involved in the protection and preservation of the country’s rich wetlands. Tina Claffey, from Birr, is an award-winning Irish nature photographer and author of 'Tapestry of Light - Ireland's bogs & wetlands as never seen before’, and ‘Portal - Otherworldly Wonders of Ireland’s bogs, wetlands and eskers’. She now features in 'A Guide for Wetlands Communities Engaging in Creative projects’, published by the Communities Wetlands Forum which was established to promote wetlands and peatlands. The compilation is seen as a major step forward in bringing Offaly’s wetlands communities together in shared purpose that has important ecological, societal and cultural benefits.

Emma McManus with her husband John at the Galway Races in July 2011. Photograph: Brenda FitzsimonsJohn McManus, the son of billionaire JP McManus, has filed a new appeal in Barbados in an attempt to quash a coroner’s finding that his wife’s December 2020 death was a result of cocaine use. Graveney Bannister, the coroner, issued findings in September 2024 that found Emma McManus’s death was cocaine-related. John McManus is now appealing a ruling from last November that refused to quash Bannister’s finding. The private report concluded that Emma McManus’s cause of death was “natural”, arising from asphyxia caused by inhalation of food material.

A further 400 people are expected to fly from Dubai to Dublin tomorrow, as foreign affairs Minister Helen McEntee said “vulnerable people” will be prioritised for charter flights. A plane carrying around 400 passengers back to Dublin departed Dubai this afternoon, marking the first direct flight from the Middle East to Ireland since Saturday. Charter flight from OmanMs McEntee also confirmed the Government has signed a contract for a charter flight from Oman to bring Irish citizens back to Dublin on Thursday. Ms McEntee said the charter flight would prioritise the most vulnerable and described it as the “first of many” if required. She confirmed that Irish citizens travelling on the charter flight from Oman to Dublin will have to pay a charge.

Irish News‘This is my fourth flight I rebooked, I didn’t think I was going to get out’ – Relief as first Irish flight from Dubai since Middle East crisis touches down

'Amazon-style' drug gangs ruled by 'fear' until discovery in prison cellThey threatened a woman and her children while dressed in police uniformsView 4 Images Mark Kirkwood, Joshua Shaw, Cole Muir and Albert Marashi (Image: Lancashire Police)A gang that ran an 'Amazon-style' warehouse to deal drugs and ruled by fear was brought down after what was found in a Liverpool prison cell. Lancashire Police said the warehouse had space for storing, producing, packaging and preparing multiple types of cannabis and cannabis products for supply. When Kirkwood and Shaw were arrested on suspicion of conspiracy to supply drugs in December 2024, a search of their phones was conducted. ‌Joshua Shaw, 33, of no fixed abode, pleaded guilty to conspiracy to supply cannabis and importation of cannabis. He pleaded guilty to further charges of conspiracy to supply drugs and conspiracy to produce drugs as well as conspiracy to commit burglary.

Mourning families began to dance at their loved ones’ graves in celebration after US/Israeli strikes targeted murderous leaders of the Islamic Republic in Iran, an Iranian in Ireland said. Picture: AP/Vahid SalemiBut anything that can topple the Iranian Islamic Republic regime is something to be deeply grateful for and celebrate, she said. She said the leadership of the Iranian Islamic Republic had been targeted, as had police involved in brutality during the protests. She asked people not to use Iranians' "name or their pain” to criticise the US/Israeli strikes on Iran that began on Saturday. From the safety of Ireland, you can’t say ‘no war with Iran’ when the Iranian people say that the Islamic Republic is not Iran.