Yet, their role in Alzheimer’s disease and related dementias (ADRDs), despite their complex, multi-factorial nature, remains largely underappreciated and understudied. Abbreviations OL: Oligodendrocyte OPC: Oligodendrocyte Progenitor Cell ADRD: Alzheimer’s Disease and Related DementiasReferences Auguste YSS, Ferro A, Kahng JA, Xavier AM, Dixon JR, Vrudhula U, et al. Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice. Contribution of amyloid deposition from oligodendrocytes in a mouse model of Alzheimer’s disease. Download referencesFunding As always, thank you to the dedicated donors supporting Alzheimer’s Disease Research, a BrightFocus Foundation program.

Source: New York Times November 17, 2024 03:16 UTC