What will happen if there is depressurization on the ISS? In fact, there has been a recent case of depressurization on the ISS in the Russian Soyuz capsule. Still, it did not lead to any catastrophic consequences (except for reputational issues for the Russian space industry). Let’s understand what will happen if another depressurization occurs and how the crew will deal with such an extreme situation. Such a breach in the ISS hull will result in an air leak at a rate of 0.009 kg/s or approximately 40 cubic meters of air per hour.