In those already addicted, the GLP-1 drugs were linked to lower risks of hospitalization, overdose and death, according to the study. A recent study strongly suggests that GLP-1 drugs such as Ozempic can help fight substance addiction. They compared people who received GLP-1 drugs with those treated with medications that lower blood sugar. WHAT THE RESEARCHERS FOUNDAl-Aly and his colleagues found that people starting the GLP-1 drugs had lower risks of developing addiction to multiple substances. She cautioned that the GLP-1 drugs don’t work the same way for all users and that they have risks that must be weighed against potential benefits.