For the first time, the majority of new HIV infections occurred outside sub-Saharan Africa last year. The report highlights the progress made in sub-Saharan Africa, where new infections have decreased by 56% since 2010. This could exacerbate the disparities in access to treatment, particularly in sub-Saharan Africa, where almost half of people living with HIV are not receiving treatment. However, she noted that infections outside sub-Saharan Africa may be more challenging to address, particularly among marginalized groups. Urgent action is needed to address the disparities in access to treatment and to protect the human rights of marginalised groups.