So, what is Simon Cowell's son illness? Simon Cowell and son Eric Cowell attend the ceremony honoring Simon Cowell with star on the Hollywood Walk of Fame on August 22, 2018 in Hollywood, California. What is Simon Cowell's son illness? There has been a rumour that Simon Cowell's son might be on the autism spectrum. Final word on Simon Cowell's so illnessWhat’s Simon Cowell’s son illness?