A higher, 100 microgram booster dose of the same vaccine drove antibody levels even higher – more than 80 times pre-boost levels. read moreBurton said it would be up to governments and regulators to gauge whether they want the enhanced level of protection that a 100 microgram dose might confer. The company said that the 100 microgram dose was generally safe and well tolerated, although there was a trend toward slightly more frequent adverse reactions. U.S. regulators authorized the 50 microgram booster of Moderna’s vaccine in October. Several studies have suggested that Moderna’s vaccine is likely to cause the heart inflammation at a higher rate.