High-fat diets are causing the immune system to significantly exaggerate the inflammatory response to sepsis. ShutterstockPeople who develop sepsis after long-term consumption of a Western diet, low in fibre and high in saturated fat and sucrose, are vulnerable to severe aggravated disease, a study released on Monday has suggested. Their findings, published on Monday in the US journal Proceedings of the National Academy of Sciences, show that mice fed a Western diet have more severe sepsis and increased mortality compared with mice on a standard diet. “Western diet is reprogramming the immune status and response to the sepsis,” the researchers wrote in their paper. But, they have said, more studies will be needed to unravel how diet-triggered changes in the immune system translate into the body’s response to sepsis.
Source: The Telegraph February 11, 2019 22:18 UTC