The condition, now known as sickle cell anemia, leads to extreme pain, difficulty with breathing, kidney failure and even strokes. Yet the protection afforded by a single copy of the sickle cell mutation against malaria kept fueling its spread. Today, over 250 generations later, the sickle cell mutation has been inherited by millions of people. Some West Africans captured in the slave trade brought the sickle cell mutation to the Americas. Frederick B. Piel, an epidemiologist at Imperial College London, said he looked forward to bigger genome-based studies on the sickle cell mutation.
Source: New York Times March 08, 2018 18:11 UTC